Space radiation-associated lung injury in a murine model
نویسندگان
چکیده
منابع مشابه
Space radiation-associated lung injury in a murine model.
Despite considerable progress in identifying health risks to crewmembers related to exposure to galactic/cosmic rays and solar particle events (SPE) during space travel, its long-term effects on the pulmonary system are unknown. We used a murine risk projection model to investigate the impact of exposure to space-relevant radiation (SR) on the lung. C3H mice were exposed to (137)Cs gamma rays, ...
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Background: Radiation-induced lung injury is a refractory side effect in lung cancer radiotherapy, the mechanism still remains unclear, hence an appropriate animal mode may become useful to investigate it. Materials and Methods: 50 female Wistar rats were randomly divided into 5 groups, average 10 rats/cage: A. control group B. 3Gy×10f C. 6Gy×5f D. 12.5Gy×1f E.15.3Gy×1f....
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Melpo Christofidou-Solomidou, Ralph A. Pietrofesa, Evguenia Arguiri, Kelly S. Schweitzer, Evgeny V. Berdyshev, Maureen McCarthy, Astrid Corbitt, Joshua S. Alwood, Yongjia Yu, Ruth K. Globus, Charalambos C. Solomides, Robert L. Ullrich, and Irina Petrache Department of Medicine, Pulmonary Allergy and Critical Care Division, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pe...
متن کاملestablishment of a rat model of radiation-induced lung injury
background: radiation-induced lung injury is a refractory side effect in lung cancer radiotherapy, the mechanism still remains unclear, hence an appropriate animal mode may become useful to investigate it. materials and methods: 50 female wistar rats were randomly divided into 5 groups, average 10 rats/cage: a. control group b. 3gy×10f c. 6gy×5f d. 12.5gy×1f e.15.3gy×1f. by different doses of r...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Lung Cellular and Molecular Physiology
سال: 2015
ISSN: 1040-0605,1522-1504
DOI: 10.1152/ajplung.00260.2014